N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine
Diethylenetriaminepentaacetic acid
CAS: 67-43-6
Molecular Formula: C14H23N3O10
N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine - Names and Identifiers
| Name | Diethylenetriaminepentaacetic acid |
| Synonyms | DTPA IDRANAL?V DTPA ACID HAMPEX ACID IDRANAL(R) V Pentetic acid COMPLEXONE V(R) DIETHYLENTRIAMINOPENTACETIC ACID DIETHYLENETRIAMINEPENTACETIC ACID Diethylenetriaminepentaacetic acid Diethylenetriamino pentaacetic acid Diethylenetriamine pentaacetic acid (DIETHYLENETRINITRILO)PENTAACETIC ACID N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine DIETHYLENETRIAMINE-N,N,N',N'',N''-PENTAACETIC ACID (CARBOXYMETHYLIMINO)BIS(ETHYLENENITRILO)TETRAACETIC ACID (Carboxymethylimino)bis(ethylenenitrilo)tetraacetic acid (CARBOXYMETHYLIMINO)BIS(ETHYLENEDINITRILO)TETRAACETIC ACID 2,2'-([(carboxymethyl)imino]bis{ethane-2,1-diyl[(carboxymethyl)imino]})diacetate (non-preferred name) |
| CAS | 67-43-6 |
| EINECS | 200-652-8 |
| InChI | InChI=1/C4H13N3.5C2H4O2/c5-1-3-7-4-2-6;5*1-2(3)4/h7H,1-6H2;5*1H3,(H,3,4) |
| InChIKey | QPCDCPDFJACHGM-UHFFFAOYSA-N |
N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine - Physico-chemical Properties
| Molecular Formula | C14H23N3O10 |
| Molar Mass | 393.35 |
| Density | 1.56 |
| Melting Point | 219-220 °C (lit.) |
| Boling Point | 517.84°C (rough estimate) |
| Flash Point | 200 °C |
| Water Solubility | 5 g/L (20 ºC) |
| Solubility | Easily soluble in hot water and alkaline solution, slightly soluble in cold water, insoluble in organic solvents such as ethanol and ether |
| Vapor Presure | 4.77E-25mmHg at 25°C |
| Appearance | White crystal |
| Color | White to almost white |
| Merck | 14,7125 |
| BRN | 1810219 |
| pKa | pK1:;pK2:2.55(+1);pK3:4.33(+2);pK4:8.60(-3);pK5,10.58 (25°C) |
| PH | 2-3 (H2O, 20℃)(saturated solution) |
| Storage Condition | room temp |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Sensitive | Easily absorbing moisture |
| Refractive Index | 1.5700 (estimate) |
| MDL | MFCD00004289 |
| Physical and Chemical Properties | Appearance: White Crystal |
| Use | Used as a complexing agent, color washing kit, acrylonitrile liquid decolorizing agent, etc |
N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine - Risk and Safety
| Risk Codes | R36 - Irritating to the eyes R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R36/37/38 - Irritating to eyes, respiratory system and skin. R20 - Harmful by inhalation R63 - Possible risk of harm to the unborn child |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S37/39 - Wear suitable gloves and eye/face protection S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 3077 9/PG 3 |
| WGK Germany | 2 |
| RTECS | MB8205000 |
| FLUKA BRAND F CODES | 3 |
| TSCA | Yes |
| HS Code | 29224995 |
| Hazard Class | 9 |
| Packing Group | III |
| Toxicity | LD50 orally in Rabbit: > 2000 mg/kg |
N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine - Upstream Downstream Industry
N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine - Reference
| Reference Show more | 1. [IF=8.071] Tan Ke et al."Improvement of the Cu and Cd phytostabilization efficiency of perennial ryegrass through the inoculation of three metal-resistant PGPR strains."Environ Pollut. 2021 Feb;271:116314 |
N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine - Nature
Open Data Verified Data
This product is white crystalline or crystalline powder. Melting point 230 ℃ (decomposition), soluble in heat and alkali solution, slightly soluble in cold water, insoluble in alcohol, ether and other organic solvents.
Last Update：2024-01-02 23:10:35
N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine - Preparation Method
Open Data Verified Data
The condensation of diethylenetriamine with chloroacetic acid gives diethylenetriamine pentaacetic acid.
Last Update：2024-03-19 20:12:08
N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine - Introduction
Used as a complexing agent, using its strong synergy, complexometric titration of molybdenum, sulfate and rare earth metals, current endpoint method for the determination of copper.
Last Update：2022-10-16 17:27:50
N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine - Use
Open Data Verified Data
It is used as a defoamer for pulping, papermaking, sewage treatment, metal cutting fluid and water-based coating. Especially in the pulp and paper industry, it can eliminate the floating pulp, and can improve the pulp washing speed, washing quality and bleaching quality, reduce the loss of good pulp, eliminate the spots on the paper, transparent point, holes, etc. The defoaming effect is good.
Last Update：2024-03-19 20:12:10
N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine - Preparation method
Open Data Verified Data
Add 283.7kg of monochloroacetic acid into the reaction vessel and stir with 220L of distilled water to dissolve. Add 300kg of 40% NaOH solution dropwise at 15 ℃ for approximately 1.5 hours. Add 51.6kg of diethylenetriamine dropwise under stirring, and control the temperature at around 20 ℃ during the dropwise addition process. Continue to add 120kg of NaOH aqueous solution (40%) dropwise and react at 40 ℃ for 10-12 hours. Cool the reaction liquid to 5-10 ℃. Drip 260L of concentrated hydrochloric acid while stirring, adjust the pH to 1.6-1.7, let it stand overnight, filter out the crystals, wash the crystals with 400L of ice water, vacuum dry to obtain about 130kg of crude product, and decolorize with distilled water to obtain pure product.
Last Update：2023-12-08 10:45:53
N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine - Reference Information
| NIST chemical information | information provided by: webbook.nist.gov (external link) |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| Introduction | diethylenetriamine pentaacetic acid (DTPA), also known as diethylenetriamine pentaacetic acid, the chelation is strong and its integration with most cations is more stable than the corresponding chelate of ethylenediaminetetraacetic acid. |
| Application | as a high-efficiency chelating agent, diethylenetriamine pentaacetic acid can be used as a color inhibitor in acrylic fiber production, paper industry, water softener, textile Auxiliaries, chelating titrant, color photography and food industry, etc., at the same time in the medical, rare earth element separation and agricultural production also has a wide range of applications. |
| Use | is used in the bleaching process of paper making as a hydrogen peroxide decomposition inhibitor. The product is a chelating titrant. As a complexing agent, it is used in the treatment of radioactive isotopes and heavy metal poisoning. used as complexing agent, color washing kit, acrylonitrile liquid decolorizing agent, etc. used as foaming agent for reducing agent plastics of aldehydes, ketones and acyl chlorides, etc. |
| production method | is obtained by reacting diethylenetriamine with monochloroacetic acid. 283.7 of monochloroacetic acid was put into a reaction kettle, and 220 L of distilled water was added, stirred and dissolved. 40% NaOH solution, 300, was added dropwise at 15 °c for about 1.5 hours. Further, 51.6 of diethylenetriamine was added dropwise with stirring, and the temperature was controlled at about 20 ° C. During the addition. The dropwise addition of 120kg aqueous NaOH (40%) was then continued. Reaction at 40 °c for 10-12 h. The reaction solution was cooled to 5-10 °c. Under stirring, 260 L of concentrated hydrochloric acid was added dropwise, the pH value was adjusted to 1.6-1.7, and the mixture was left overnight. The crystals were filtered off, washed with 400 L of ice water, and dried under vacuum to obtain a crude product of about 130. Pure product was obtained by destaining with distilled water. |
Last Update：2024-04-09 15:16:52
![N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine](http://res.chembk.com/assets/str/2d/6/67/67-43-6.png)
Supplier List
Spot supply
Product Name: Diethylenetriaminepentaacetic acid Request for quotationCAS: 67-43-6
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: Diethylenetriaminepentaacetic acid Request for quotationCAS: 67-43-6
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: Diethylenetriaminepentaacetic acid Request for quotation
CAS: 67-43-6
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 67-43-6
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: Trolamine Impurity 10 (Diethylenetriaminepentaacetic Acid) Visit Supplier Webpage Request for quotationCAS: 67-43-6
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Diethylenetriaminepentaacetic acid Request for quotation
CAS: 67-43-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 67-43-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Spot supply
Product Name: DTPA Visit Supplier Webpage Request for quotationCAS: 67-43-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple Specifications
Product Name: Diethylenetriaminepentaacetic acid Request for quotationCAS: 67-43-6
Tel: 86-10-10086 81625225
Email: yeqim@boyechemicals.com
Mobile: 86-15387090420
QQ: 1377812380
Wechat: 15387090420
Spot supply
Product Name: Diethylenetriaminepentaacetic acid Request for quotationCAS: 67-43-6
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3787852685
Spot supply
Product Name: Diethylenetriaminepentaacetic acid Request for quotationCAS: 67-43-6
Tel: +86-17551318830
Email: r@reformchem.com
Mobile: +86-17551318830
QQ: 3785839865
Product Name: Diethylenetriaminepentaacetic acid Request for quotation
CAS: 67-43-6
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
CAS: 67-43-6
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Wechat: 17505222756
Spot supply
Product Name: Trolamine Impurity 10 (Diethylenetriaminepentaacetic Acid) Visit Supplier Webpage Request for quotationCAS: 67-43-6
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Product Name: Diethylenetriaminepentaacetic acid Request for quotation
CAS: 67-43-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
CAS: 67-43-6
Tel: 0086-551-65418684
Email: sales@tnjchem.com
info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Spot supply
Product Name: DTPA Visit Supplier Webpage Request for quotationCAS: 67-43-6
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Multiple Specifications
Product Name: Diethylenetriaminepentaacetic acid Request for quotationCAS: 67-43-6
Tel: 86-10-10086 81625225
Email: yeqim@boyechemicals.com
Mobile: 86-15387090420
QQ: 1377812380
Wechat: 15387090420
View History
Raw Materials for N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine